Born tuscan in '65 from two journalists, he started traveling very young: from Florence to Venice and New York before he landed in Milan as a teenager. At the beginning of the 80s he attended a workshop on reportage held by Leonard Freed, a Magnum photographer. From then on he never stopped observing life without some sort of camera.
In 1986 Francesco started working as a Location Scout for Politecne, an italian Film Production company. In the following decade, as Massimo Magri's Assistant Director, he's been in charge of a number of documentary, commercial and industrial film sets around the world.
After graduating from the Intensive Filmmaking Program at New York University, Nencio directed commercials for Coca Cola, Kodak, Martini, Mc Donald's, Swatch, Tuborg, Volkswagen.

Private Eye, his first monographic exhibition as a photographer, opened at L'Affiche Gallery in Milan on February 17, 2005.
I Non Luoghi, a documentary project on modern metropolises inspired by the essay of anthropologist's Marc Augé on NonPlaces, was published by Silvana Editoriale and awarded the First Absolute Prize at Orvieto Foto Festival in 2006.
Be Someone, Nencini's colourful reportage behind the scenes of Show Biz, won a Prize at Toscana Foto Festival and his work was also nominated in the Abstract Category at The International Colour Awards in the United States.
Francesco's work has been published by: Black & White Photography U.K., Il Fotografo, Digital Camera Magazine, Cult Frame, Fotopratica, Nikon's Sguardi, Virgilio and Vision China.
His last collective exhibitions include Voies Off, Descubrimientos PHE 08, CliCiak, Occhi di Scena, Arte Laguna, Prima Visione (Galleria Belvedere, Milan), Kaibakh Festival, Foiano Fotografia.